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Peptipedia
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LongevityElevated cautionResearch only

NAD+

NAD · NAD plus · nicotinamide adenine dinucleotide · β-NAD · coenzyme I

Clinics drip it. The vial in Mix is a shot, and it can sting or flush. People use it for energy talks. It does not turn the clock back.

Usual range

25–200 mg

Schedule

2–5× weekly subq, or a short daily block

Half-life

Minutes in plasma; tissue effects are what people are chasing

How it is used

Not a peptide. A molecule your cells already use for energy.

Subcutaneous · also Intramuscular

Morning or early afternoon. Subq is the home-vial route in this calculator. IV (often 250–750 mg over hours) belongs in a clinic — a fast IV push is what causes chest tightness and panic-like flushing.

4–8 week blocks are common in anecdotal protocols, then reassess energy and sleep — not a forever daily shot.

How to mix this vial

Typical vial 500 mg · 1 mL BAC

500 mg + 5 mL bacteriostatic water → 100 mg/mL. 50 mg = 50 units; 100 mg = 100 units (1 mL). NAD+ stings — a slower push and a little extra water help. IV bags are a clinic procedure, not a home Mix.

Lyophilized: fridge or freezer. After mixing, fridge and use promptly; solutions can yellow and lose potency.

Side effects

  • Injection-site burn
  • Flushing
  • Nausea and cramping
  • Chest tightness or shortness of breath if pushed too fast (especially IV)
  • Headache
  • Fatigue the first sessions

Who should skip this

  • Pregnancy
  • Unstable heart disease
  • Active cancer unless a clinician is directing NAD-related care
  • Do not self-administer IV

Nutrition note

Protein and resistance training still do more for mitochondria than a vial. Niacin flush from oral B3 is a different molecule — do not stack high-dose niacin on injection day until you know how you react.

Stacks

Often stacked with

Endogenous molecule, unapproved as an anti-aging drug. Clinic IV and compounded subq are not interchangeable. Mix math here is for a subcutaneous vial, not an infusion.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.