MOTS-c
Mitochondrial ORF of the 12S rRNA type-c
Mitochondrial peptide studied for insulin sensitivity and exercise mimicry.
A 16-amino-acid peptide encoded in mitochondrial DNA. Preclinical work links it to AMPK activation, metabolic flexibility, and exercise-like adaptations.
Usual range
5–15 mg
Schedule
2–3× weekly
Half-life
Hours; usually 2–3× weekly
How it is used
Mitochondrial peptide studied for insulin sensitivity and exercise mimicry.
Subcutaneous
Morning on training days, or 2–3 set weekdays.
4–8 weeks. Longevity users sometimes pulse monthly.
How to mix this vial
Typical vial 10 mg · 2 mL BAC
10 mg + 2 mL → 5 mg/mL. 5 mg = 100 units (full 1 mL) or split vials accordingly.
Fridge. Some keep lyophilized frozen.
Side effects
- Flushing
- Injection-site itch
- Transient fatigue
Who should skip this
- Pregnancy
- Uncontrolled illness
Nutrition note
Carbohydrate around training is fine. This is a metabolic helper, not a diet.
Stacks
Often paired with
Human dosing is extrapolated and inconsistent across sources.
Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.