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MetabolicElevated cautionApproved molecule

Tirzepatide

Mounjaro · Zepbound · LY3298176

A weekly dual-agonist many people compare with semaglutide for appetite.

A dual incretin agonist approved for T2D and weight management. Typically more weight loss than semaglutide in trials, with similar GI titration rules.

Usual range

2.5–15 mg

Schedule

Once weekly

Half-life

~5 days

How it is used

Dual GIP/GLP-1 agonist. Stronger weight effect, same titration logic.

Subcutaneous

Same weekday. Rotate sites.

Ongoing under care. Stay at the lowest effective dose.

How to mix this vial

Typical vial 10 mg · 2 mL BAC

10 mg + 2 mL → 5 mg/mL. 2.5 mg = 50 units. Confirm vial milligrams before mixing.

Fridge. Do not freeze. Branded pens follow label.

Side effects

  • Nausea
  • Vomiting
  • Constipation
  • Reflux
  • Gallbladder disease
  • Muscle loss if under-eating protein

Who should skip this

  • MTC / MEN2
  • Pregnancy
  • Serious GI disease

Nutrition note

Four small protein-forward meals beat two large ones. Stop eating at first fullness. Resistance training is non-negotiable.

Stacks

Often paired with

Approved drug. Compounded tirzepatide is not Zepbound/Mounjaro.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.