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CognitiveStandard cautionResearch only

Semax

ACTH 4-10 analog

A nasal peptide some countries use for focus. Not FDA-approved.

A synthetic ACTH fragment used clinically in Russia for ischemic stroke and cognitive support. Intranasal use is the standard research route. Increases BDNF in animal work.

Usual range

200–900 mcg

Schedule

1–2× daily, nasal

Half-life

Short; effects last hours

How it is used

Russian ACTH analog used as a nasal nootropic.

Intranasal

Morning and early afternoon. Avoid late evening if stimulating.

10–14 days on, 2–4 weeks off; or weekdays only.

How to mix this vial

Typical vial 10 mg · 5 mL BAC

Often supplied as nasal drops/spray. If lyophilized: 10 mg + 5 mL saline → 2 mg/mL. 300 mcg = 0.15 mL.

Fridge. Nasal solutions: follow pharmacy beyond-use date.

Side effects

  • Nasal irritation
  • Restlessness
  • Headache

Who should skip this

  • Uncontrolled hypertension (relative)
  • Pregnancy

Nutrition note

Caffeine stacks additively — start without extra stimulants.

Stacks

Often paired with

Approved in Russia; not FDA-approved.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.