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Retatrutide

LY3437943 · triple agonist

An investigational triple-agonist. Not an everyday starter.

A triple incretin/glucagon agonist in late-stage trials with very large weight-loss signals. Not approved. Doses below are trial-range education only.

Usual range

1–12 mg

Schedule

Once weekly (trial-style)

Half-life

~6 days

How it is used

Investigational GIP/GLP-1/glucagon triple agonist.

Subcutaneous

Weekly, consistent day.

Trial durations were months, always titrated.

How to mix this vial

Typical vial 10 mg · 2 mL BAC

Research vials vary. Example: 10 mg + 2 mL → 5 mg/mL.

Fridge, research handling.

Side effects

  • GI effects
  • Elevated heart rate
  • Lean-mass loss
  • Unknown long-term profile

Who should skip this

  • Pregnancy
  • MTC/MEN2 (class caution)
  • Unsupervised research use

Nutrition note

Same GLP-1 kitchen: small, bland, protein-first. Watch resting heart rate.

Not approved. Peptipedia lists trial-range figures so the titration idea is visible — not so you can source it.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.