PT-141
Bremelanotide · Vyleesi
Nausea and flushing are common. It can raise blood pressure, so it is a skip with uncontrolled high blood pressure. It is not a hormone replacement.
Usual range
0.5–1.75 mg
Schedule
As needed, ≥48 h apart (max 8×/month branded)
Half-life
~2–3 hours (effect 6–12 h)
How it is used
People use this when they want desire. Taken ahead of time, not every day.
Subcutaneous
45–60 minutes before desired effect. Test a small dose first — nausea is common.
As needed. Branded label: no more than one dose in 24 h, eight per month.
How to mix this vial
Typical vial 10 mg · 1 mL BAC
Branded Vyleesi is 1.75 mg autoinjector. Compounded 10 mg + 2 mL → 5 mg/mL. 1 mg = 20 units.
Fridge for compounded; branded autoinjectors follow label.
Side effects
- Nausea (very common)
- Flushing
- Headache
- Darkening of gums/skin with repeated use
- Blood pressure changes
Who should skip this
- Uncontrolled hypertension
- Cardiovascular disease
- Pregnancy
Nutrition note
Take on a lighter stomach. Ginger may help nausea. Alcohol worsens it.
Stacks
Vyleesi 1.75 mg is the approved female HSDD dose. Men in research settings often start lower because of nausea. Compounded PT-141 is not Vyleesi.
Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.