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KPV

Lys-Pro-Val · α-MSH fragment

Anti-inflammatory tripeptide used in gut and skin protocols.

A C-terminal fragment of α-MSH studied for potent anti-inflammatory effects without melanocortin pigmentation. Used anecdotally for IBD-like symptoms, gut barrier, and inflammatory skin.

Usual range

200–1000 mcg

Schedule

Once or twice daily

Half-life

Short; 1–2× daily

How it is used

Anti-inflammatory tripeptide used in gut and skin protocols.

Subcutaneous · also Oral

Empty stomach if oral; any time if subq.

4–8 weeks aligned with a gut-healing block.

How to mix this vial

Typical vial 10 mg · 2 mL BAC

10 mg + 2 mL → 5 mg/mL. 500 mcg = 10 units.

Refrigerate after mixing.

Side effects

  • Mild nausea
  • Injection-site itch

Who should skip this

  • Pregnancy
  • Uninvestigated GI bleeding

Nutrition note

Low-irritant meals. Limit alcohol, NSAIDs, and ultra-processed oils during a gut block.

Often paired with

Human trial data is sparse. Not a substitute for IBD care.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.