Kisspeptin-10
Kp-10 · metastin fragment
GnRH upstream signal used in reproductive-axis research.
A decapeptide that stimulates GnRH neurons, in turn LH/FSH. Researched as a diagnostic and as a more physiologic trigger of the reproductive axis than direct GnRH in some settings.
Usual range
50–200 mcg
Schedule
2–3× weekly or as a stimulation test
Half-life
Minutes to ~30 min
How it is used
GnRH upstream signal used in reproductive-axis research.
Subcutaneous
Morning. Pulsatile logic matters — this is not a daily blast.
Short diagnostic or 4–8 week experimental blocks under endocrine care.
How to mix this vial
Typical vial 5 mg · 2 mL BAC
5 mg + 2 mL → 2.5 mg/mL. 100 mcg = 4 units.
Fridge. Short-dated.
Side effects
- Flushing
- Mood change
- LH/testosterone swings
- Injection-site irritation
Who should skip this
- Hormone-sensitive cancers
- Pregnancy
- Precocious puberty contexts
Nutrition note
Sleep, body-fat, and energy availability drive the axis more than this peptide.
An endocrine tool, not a lifestyle peptide. Misuse can desynchronize the axis.
Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.