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DSIP

Delta Sleep-Inducing Peptide

Nonapeptide studied for sleep architecture.

A nonapeptide isolated from cerebral venous blood in the 1970s. Anecdotally used for sleep onset and reducing nighttime cortisol. Results are highly individual.

Usual range

100–300 mcg

Schedule

Nightly, 30–60 min before bed

Half-life

Minutes in plasma; CNS effect may last the night

How it is used

Nonapeptide studied for sleep architecture.

Subcutaneous

Lights-down. Dark room, no screens.

7–14 nights, then reassess tolerance.

How to mix this vial

Typical vial 5 mg · 2 mL BAC

5 mg + 2 mL → 2.5 mg/mL. 100 mcg = 4 units.

Fridge. Sensitive peptide — keep cold.

Side effects

  • Vivid dreams
  • Morning grogginess
  • Paradoxical alertness

Who should skip this

  • Narcolepsy (relative)
  • Pregnancy

Nutrition note

No heavy meal within 2 hours of bed. Magnesium glycinate is a reasonable non-peptide adjunct.

Stacks

Often paired with

Human evidence is old and mixed. Sleep hygiene still dominates.

Peptipedia is an educational calculator, not medical advice. Many catalog entries are unapproved for human use. Approved molecules have labels that outrank this app. Do not use this to self-prescribe. Consult a licensed clinician. Not for anyone under 18, pregnant, or being treated for cancer.